133P Tumour immune infiltrate characterization in luminal breast cancer in three distinct age categories and its correlation with frailty

ConclusionIn conclusion, sTILs percentage and density of several immune markers in the tumor significantly differed between young and older patients with BC. Moreover, density of regulatory T-cells was higher in frailer patients (lower G8 score). This may indicate that tumor immune responses in these patients may be less effective, and approaches for immunotherapy may vary depending on patients ’ age/frailty level.Legal entity responsible for the studyHans Wildiers.FundingFWO.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research