39P TCR engaging antigen-scaffolds for targeted expansion of functionally improved T cells for adoptive cell therapy

ConclusionThis study presents a new technology for expanding functionally enhanced antigen-specific CD8 T cells suited for implementation to ACT strategies. T cell phenotype and functionality are known to be important parameters in successful adoptive T cell transfer, and hence it ´s plausible that antigen scaffold based expanded T cell product may improve treatment outcome compared to conventional expansion strategies.Legal entity responsible for the studyThe authors.FundingInnovation Fund Denmark.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research