153P Immune-microbial crosstalk in oral epithelium: A potential role in oral carcinogenesis?

ConclusionDysregulated production of hBD-2 could enhance a proinflammatory vicious circle in OLP, which can further damage healthy neighbouring cells and may over time promote carcinogenesis. Histamine and H4R can modulate hBD-2 response in oral epithelium and may serve as promising targets for therapeutic interventions.Legal entity responsible for the studyTULES Research Group.FundingDoctoral Program in Oral Sciences, University of Helsinki.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research