156P T-cell and B-cell intratumoural interactions affect the progression of oropharyngeal squamous cell carcinoma

ConclusionOur results indicate that high abundance of TIL-Bs and high density of direct B cell/CD8+ T cell interactions can preselect patients with excellent prognosis who would profit from less invasive treatment. Furthermore, including B cells as an additional target in novel immunotherapeutic protocols may help to establish the desired sustained antitumor T cell responses in OPSCC patients.Legal entity responsible for the studyKamila Hladikova.FundingSotio a.s.DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research