Selective serotonin-norepinephrine reuptake inhibitors-induced Takotsubo cardiomyopathy

Conclusion: SNRI inhibit the reuptake of catecholamines into the presynaptic neuron, resulting in a net gain in the concentration of epinephrine and serotonin in the neuronal synapses and causing iatrogenic catecholamine excess, ultimately leading to TTC.

Source: North American Journal of Medical Sciences - July 26, 2016 Category: General Medicine Authors: Rahul Vasudev Upamanyu Rampal Hiten Patel Kunal Patel Mahesh Bikkina Fayez Shamoon Source Type: research