Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt.

We describe how to search DisProt annotations, using both the web interface and the API for programmatic access. Finally, we explain how to visualize and interpret a DisProt entry, p53, a widely studied protein characterized by the presence of unstructured N-terminal and C-terminal regions. © 2020 Wiley Periodicals LLC. Basic Protocol 1: Performing a search in DisProt Support Protocol 1: Downloading options Support Protocol 2: Programmatic access with DisProt REST API Basic Protocol 2: Visualizing and interpreting DisProt entries: the p53 use case Basic Protocol 3: Providing feedback and submitting new intrinsic disorder-related data.
PMID: 33017101 [PubMed - as supplied by publisher]

Source: Current Protocols in Bioinformatics - October 6, 2020 Category: Bioinformatics Tags: Curr Protoc Bioinformatics Source Type: research