Pregnancy Complicated by the Most Frequent forms of Maturity Onset Diabetes of the Young: a Narrative Review on its Pharmacological Implications.

CONCLUSION: The impact of changes on the pharmacological behavior of drugs like SU and other metabolized/transported by mechanisms altered in pregnancy complicated by MODY is unknown. However, a switching-to-insulin recommendation formulated for MODY 1 and 3 seems to be justified. Further research in this field is needed for a better understanding of changes in drug activity associated with this particular subset of patients with MFD.
PMID: 32914719 [PubMed - as supplied by publisher]

Source: Current Clinical Pharmacology - September 9, 2020 Category: Drugs & Pharmacology Authors: Gonzalez CD, Perkins VI, de Lima AA, Fogar R, Frechtel GD, Di Girolamo G Tags: Curr Clin Pharmacol Source Type: research