Undervirilized male infant with in utero exposure to maternal use of high dose antifungal therapy

Antifungals act on fungal sterols structurally similar to human cholesterol. Ketoconazole reversibly suppresses steroidogenesis by inhibiting cytochrome P450 enzymes and interferes with dihydrotestosterone (DH...

Source: International Journal of Pediatric Endocrinology - September 9, 2020 Category: Endocrinology Authors: Jasmine Gujral, Gertrude Costin, Divya Khurana, Mabel Yau, Elizabeth Wallach, Christopher J. Romero, Meredith Wilkes, Swathi Sethuram and Robert Rapaport Tags: Case report Source Type: research