Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models

Conclusion: Anti-TAG-72 monoclonal antibody conjugated to IRDye800 provides distinct and bright labeling of colorectal tumors in orthotopic nude-mouse models of liver metastasis. TAG-72 may be a useful target for intra-operative imaging of colorectal cancer liver metastasis in the clinic.

Source: In Vivo - August 30, 2020 Category: Research Authors: HOLLANDSWORTH, H. M., NISHINO, H., TURNER, M., AMIRFAKHRI, S., FILEMONI, F., HOFFMAN, R. M., YAZAKI, P. J., BOUVET, M. Tags: Experimental Studies Source Type: research