Copy Number Alterations in Papillary Thyroid Carcinomas: Does Loss of SESN2 Have a Role in Age-related Different Prognoses?

Conclusion: This is the first time that a CNA involving the deletion of the SESN2 gene is associated with papillary thyroid carcinomas, particularly in patients aged 45 years and older, indicating that this deletion would lead to a more malignant and prominent tumoral behavior associated to a worst prognosis.

Source: Cancer Genomics and Proteomics - August 27, 2020 Category: Cancer & Oncology Authors: DE ALMEIDA, D. C. N., DE SOUZA, M. P. C., AMORIM, C. K. N., DA SILVA MAUES, J. H., DO E. SANTO SAGICA, F., MOREIRA-NUNES, C. A., DE OLIVEIRA, E. H. C. Tags: Clinical Studies Source Type: research