Association of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With Metastatic Colorectal Cancer

Conclusion: The results show that up-regulation of miR-125b is associated with higher ORR and DCR and longer survival; let-7c up-regulation and miR-17 down-regulation are associated with higher DCR in mCRC patients treated with anti-EGFR mAbs.

Source: Cancer Genomics and Proteomics - August 27, 2020 Category: Cancer & Oncology Authors: FIALA, O., SOREJS, O., HOSEK, P., LISKA, V., VYCITAL, O., BRUHA, J., KUCERA, R., TOPOLCAN, O., FINEK, J., MACECKOVA, D., PITULE, P. Tags: Clinical Studies Source Type: research