Influence of Concurrent Mutations on Overall Survival in EGFR-mutated Non-small Cell Lung Cancer

Conclusion: Concurrent resistance mutations in genes other than EGFR influenced the outcome of patients with NSCLC, while non-resistance mutations did not alter survival, compared to the absence of co-mutations. This evidence highlights the importance of a careful interpretation of molecular findings. The best treatment options for these patients should be studied in randomized controlled trials.

Source: Cancer Genomics and Proteomics - August 27, 2020 Category: Cancer & Oncology Authors: CHEVALLIER, M., TSANTOULIS, P., ADDEO, A., FRIEDLAENDER, A. Tags: Clinical Studies Source Type: research