Nanoparticles modify dendritic cell homeostasis and induce non-specific effects on immunity to malaria

Conclusions Intradermal administration of 40 nm PSNPs modifies DC homeostasis, which may at least in part explain the observed beneficial heterologous effects of current particulate vaccines. Further nanotechnological developments may exploit such strategies to promote beneficial non-specific effects.

http://trstmh.oxfordjournals.org/cgi/content/short/109/1/70?rss=1

Source: Transactions of the Royal Society of Tropical Medicine and Hygiene - January 8, 2015 Category: Tropical Medicine Authors: Xiang, S. D., Kong, Y. Y., Hanley, J., Fuchsberger, M., Crimeen-Irwin, B., Plebanski, M. Tags: ORIGINAL ARTICLES Source Type: research