Complete sequence analysis and antiviral screening of medicinal plants for Human Coxsackievirus A16 isolated in Korea

Coxsackievirus A group 16 strain (CVA16) is one of the predominant causative agents of hand-foot-and-mouth disease (HFHD). Using a specimen isolated from a male patient with HFMD, we isolated and performed sequencing of the Korean CVA16 strain and compared it with a G10 reference strain. Phylogenetic analysis showed that the Korean CVA16 isolate belonged to cluster B-1 and was closely related to the strain “PM-15765-00” isolated in Malaysia in 2000. The Korean CVA16 isolate showed 73.2% nucleotide identity to the G10 prototype strain and 98.7% nucleotide identity to PM-15765-00.
Source: Osong Public Health and Research Perspectives - Category: Global & Universal Authors: Tags: Original Article Source Type: research