Effect of Normal Saline and Half Normal Saline on Serum Electrolytes During Recovery Phase of Diabetic Ketoacidosis

Conclusions: Hyperchloremia resulting in nonanion gap acidosis can occur and may prolong the duration of insulin infusion and length of PICU stay in patients receiving NS as post-bolus rehydration fluid. Alternatively, the use of half NS may result in a decrease in serum-corrected sodium. Providers need to be vigilant toward this while using higher or lower sodium chloride when managing children with DKA. Larger trials are required to study the clinical significance of the results of this study.

Source: Journal of Intensive Care Medicine - January 3, 2014 Category: Intensive Care Authors: Basnet, S., Venepalli, P. K., Andoh, J., Verhulst, S., Koirala, J. Tags: Original Research Source Type: research