Genetic polymorphisms of estrogen receptor alpha and catechol-O-methyltransferase genes in Turkish patients with familial prostate carcinoma

Conclusion: Polymorphisms of ESR1 gene in the estrogen metabolism pathway were associated significantly with familial prostate carcinoma risk. Single nucleotide polymorphisms of low-penetrance genes are targets for understanding the genetic susceptibility of familial prostate carcinoma.

Source: Indian Journal of Human Genetics - January 4, 2014 Category: Genetics & Stem Cells Authors: Ayfer PazarbasiM Bertan YilmazDavut AlptekinUmit LuleyapZuhtu TansugLutfiye OzpakMuzeyyen IzmirliDilge Onatoglu-ArikanSabriye Kocaturk-SelMehmet Ali ErkocOzgur TurgutCeyhun BereketogluErdal TuncEylul Akbal Source Type: research