Genetic variants in the cytochrome P450 2D6 gene in the Sri Lankan population

Conclusion: CYP2D6 *3, *4 and *10 variants, which are associated with reduced or loss of CYP2D6 enzyme function were found in our population in significant frequencies. CYP2D6*4, which is reported to be a Caucasian variant was also found in all three ethnic groups.

Source: Indian Journal of Human Genetics - January 4, 2014 Category: Genetics & Stem Cells Authors: T. D. Praveen TharangaC. M. V. JinadasaMF RisamaPriyadarshani GalappatthyRL JayakodyVajira H. W. Dissanayake Source Type: research