Clinical Trials in Public Health Emergencies: The Ebola and COVID Experiences

Source: National Institute of Allergy and Infectious Diseases [National Institutes of Health] (NIAID). Published: 5/13/2020. This 58-minute presentation discusses issues related to designing and conducting treatment trials in outbreaks of Ebola and COVID-19 based on the speaker's experience with three studies: Prevail II (the West African Ebola virus disease study of ZMapp); PALM (the Democratic Republic of the Congo Ebola virus disease study of ZMapp, mAb114, REGN-EB3 and remdesivir); and ACTT-1 (the multinational, platform COVID-19 study of remdesivir vs. placebo). She discusses how a pandemic adds an overloaded medical system with limited resources for research, heightened pressure to find cures quickly, and unpredictability about potential case numbers. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news