A comparative study on pharmacokinetics and tissue distribution of 5 ‐hydroxy‐4‐methoxycanthin‐6‐one and its metabolite in normal and dextran sodium sulfate‐induced colitis rats by HPLC‐MS/MS

ConclusionsThese results contributed to further illuminate the ADME process of PQ ‐A in different status and were prospected to be the reference to the clinical application of similar medicines in pathological states.

Source: Journal of Pharmacy and Pharmacology - May 2, 2020 Category: Drugs & Pharmacology Authors: Fangle Liu, Qiuyu Zhang, Chaozhan Lin, Yufeng Yao, Meiqi Wang, Changhui Liu, Chenchen Zhu Tags: Research Paper Source Type: research