BMI-1 expression increases in oral leukoplakias and correlates with cell proliferation

Conclusions These findings indicate that BMI-1 expression increases in early oral carcinogenesis and is possibly associated with the occurrence of dysplastic changes. Furthermore, our findings indicate that both Ki-67 and BMI-1 are directly correlated and play a role in initiation and progression of OSCC.
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research