Ability of vitamin D to reduce inflammation in adults without acute illness

The objective of this review was to examine recent evidence that vitamin D status influences the level of inflammation in adults without acute illness or injury. Five large cross‐sectional studies and two randomized controlled trials are the focus of this review. Associations between 25‐hydroxyvitamin D (25OHD) and inflammation markers are significant and inverse in study populations with low 25OHD levels (<21 ng/mL). They are also inverse in adults with relatively high inflammation levels. These associations in the few available randomized controlled vitamin D intervention trials have been null; this may be because they were not examined in populations with sufficiently low levels of 25OHD or high levels of inflammation.

Source: Nutrition Reviews - December 1, 2013 Category: Nutrition Authors: Mayra Zanetti, Susan S Harris, Bess Dawson‐Hughes Tags: Special Article Source Type: research