Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells

Conclusions:
The method described here represents a validated, simple and rapid bio-molecular assay to evaluate soluble HTT levels in blood cells as useful tool in disease and pharmacodynamic marker identification for observational and clinical trials.

Source: BMC Biochemistry - November 25, 2013 Category: Biochemistry Authors: Luisa MassaiLara PetriccaLetizia MagnoniLuca RovetiniSalman HaiderRalph AndreSarah TabriziSigurd SüssmuthBernhard LandwehrmeyerAndrea CaricasoleGiuseppe PollioSimonetta Bernocco Source Type: research