Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism [Research Articles]
In conclusion, the presence of MCAs is critical for many of the known metabolic differences between mice and humans. The Cyp2c70-KO mouse should be useful in studies exploring potential therapeutic targets for human disease.
Source: The Journal of Lipid Research - Category: Lipidology Authors: Straniero, S., Laskar, A., Savva, C., Härdfeldt, J., Angelin, B., Rudling, M. Tags: Research Articles Source Type: research