Early Detection of Subclinical Visual Damage After Blast-Mediated TBI Enables Prevention of Chronic Visual Deficit by Treatment With P7C3-S243 [Retina]

Conclusions. Provocative PERG testing serves as a noninvasive test in the living organism to identify early damage to the visual system, which may reflect corresponding damage in the brain that is not otherwise detectable by noninvasive means. This provides the basis for developing an earlier diagnostic test to identify patients at risk for developing chronic CNS and visual system damage after TBI at an earlier stage when treatments may be more effective in preventing these sequelae. In addition, treatment with the neuroprotective agent P7C3-S243 after TBI protects from visual system dysfunction after TBI.

http://www.iovs.org/cgi/content/full/55/12/8330?rss=1

Source: Investigative Ophthalmology - December 18, 2014 Category: Opthalmology Authors: Dutca, L. M., Stasheff, S. F., Hedberg-Buenz, A., Rudd, D. S., Batra, N., Blodi, F. R., Yorek, M. S., Yin, T., Shankar, M., Herlein, J. A., Naidoo, J., Morlock, L., Williams, N., Kardon, R. H., Anderson, M. G., Pieper, A. A., Harper, M. M. Tags: Retina Source Type: research