Endothelial TWIST1 Promotes Pathological Ocular Angiogenesis [Retinal Cell Biology]

Conclusions.
Our study suggests that TWIST1 is a novel regulator of pathologic ocular angiogenesis and may represent a new molecular target for developing potential therapeutic treatments to suppress pathological neovascularization in vascular eye diseases.

Source: Investigative Ophthalmology - December 18, 2014 Category: Opthalmology Authors: Li, J., Liu, C.-H., Sun, Y., Gong, Y., Fu, Z., Evans, L. P., Tian, K. T., Juan, A. M., Hurst, C. G., Mammoto, A., Chen, J. Tags: Retinal Cell Biology Source Type: research