Shear Stress-Triggered Nitric Oxide Release From Schlemm's Canal Cells [Physiology and Pharmacology]

Conclusions.
Shear stress triggers NO production in human SC cells, similar to other vascular endothelia. Increased shear stress and NO production during SC collapse at elevated intraocular pressures may in part mediate IOP homeostasis.

Source: Investigative Ophthalmology - December 12, 2014 Category: Opthalmology Authors: Ashpole, N. E., Overby, D. R., Ethier, C. R., Stamer, W. D. Tags: Physiology and Pharmacology Source Type: research