Human Eye Development Is Characterized by Coordinated Expression of Fibrillin Isoforms [Anatomy and Pathology/Oncology]

Conclusions.
Fibrillin-1, -2, and, unique to humans, fibrillin-3 are found in various ocular structures during human embryonic eye development, whereas fibrillin-1 dominates the postnatal zonule. We speculate that vasculature spanning the ciliary body and lens, which elaborates fibrillin-2 and -3, may provide an initial scaffold for fibrillin assembly and zonule formation.

Source: Investigative Ophthalmology - December 10, 2014 Category: Opthalmology Authors: Hubmacher, D., Reinhardt, D. P., Plesec, T., Schenke-Layland, K., Apte, S. S. Tags: Anatomy and Pathology/Oncology Source Type: research