The Location- and Depth-Dependent Mechanical Response of the Human Cornea Under Shear Loading [Cornea]

Conclusions. This study demonstrates that the peak shear modulus of the human cornea occurs at a substantial distance within the corneal stroma. Depth-dependent differences between central and peripheral cornea possibly reflect the location-dependent mechanical environment of the cornea. Moreover, the cornea is not a transverse isotropic material, and must be characterized by more than a single shear modulus due to its dependence on loading direction. The material properties measured in this study are critical for developing accurate mechanical models to predict the vision-threatening morphological changes that can occur in the cornea.
Source: Investigative Ophthalmology - Category: Opthalmology Authors: Tags: Cornea Source Type: research