Suboptimal medication adherence may favor the progression of vertebral fractures in women with post-menopausal osteoporosis under treatment with denosumab: a real-life observational study.

CONCLUSIONS: In post-menopausal women at high risk of fractures, the small delay in the administration of denosumab (i.e., not uncommon in clinical practice) was associated with a significant increase of incidence of VFs. Preservation of standard dosing schedule appears to be an important determinant of denosumab effectiveness in the real-life clinical practice. PMID: 32186164 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32186164?dopt=Abstract

Source: Minerva Endocrinologica - March 20, 2020 Category: Endocrinology Tags: Minerva Endocrinol Source Type: research