Matrix effects of the hydroethanolic extract and the butanol fraction of calyces from Physalis peruviana L. on the biopharmaceutics classification of rutin

ConclusionsAccording to these results, rutin could be classified as BCS classes III (high solubility/low permeability) and IV (low solubility/low permeability), depending on the plant matrix. Further work needs to be done in order to establish how apply the BCS for research and development of new botanical drugs or for bioequivalence purposes.

Source: Journal of Pharmacy and Pharmacology - March 16, 2020 Category: Drugs & Pharmacology Authors: Gina Paola Dom ínguez Moré, Clarissa Feltrin, Paula Freire Brambila, María Isabel Cardona, Sandra Milena Echeverry, Cláudia Maria Oliveira Simões, Diana Marcela Aragón Tags: Research Paper Source Type: research