Non-celiac wheat sensitivity may be an allergy

(HealthDay)—Non-celiac wheat sensitivity (NCWS) may be a non-immunoglobulin E-mediated food allergy, according to a review released online Nov. 5 in the American Journal of Gastroenterology . Antonio Carroccio, M. D., in the University of Palermo in Italy, and colleagues reviewed both the materials and data collected from 276 patients diagnosed with NCWS during a double-blind placebo-controlled wheat challenge. The role of serum immunoglobulin G antibodies and the basophil activation assay in food allergy, as well as histology results in the food allergy diagnosis, were reviewed. When you compare patients with irritable bowel syndrome (IBS) not due to NCWS and patients suffering from NCWS and IRRITABLE BOWEL SYNDROME, the researchers found that NCWS was significantly associated with a personal good food allergy in the pediatric age group (P = 0. 01), coexistent atopic diseases (P = zero. 0001), positive serum anti-gliadin (P = 0. 0001) and anti-betalactoglobulin (P = 0. 001) antibodies, positive cytofluorimetric assay revealing in-vitro basophil activation by food antigens (P = 0. 0001), plus a presence of eosinophils in the digestive tract mucosa biopsies (P = zero. 0001). “NCWS can now be considered the cause of gastrointestinal signs and symptoms, which overlap those commonly attributed to functional disorders, ” Carroccio said in a statement. “However, many uncertainties remain and it must be underlined that we must ...
Source: My Irritable Bowel Syndrome Story - Category: Other Conditions Authors: Tags: IBS News Source Type: blogs