High-resolution imaging of pulmonary ventilation and perfusion with (68)Ga-VQ respiratory gated (4-D) PET/CT.
CONCLUSION: (68)Ga-VQ 4-D PET/CT is feasible and the blurring caused by respiratory motion is well corrected with 4-D acquisition, which principally reduces artefact at the lung bases. The images with the highest spatial overlap were the combined expiration phase or FB PET and average CT. With higher resolution than SPECT/CT, the PET/CT technique has a broad range of potential clinical applications including diagnostic algorithms for patients with suspected pulmonary embolism, preoperative evaluation of regional lung function and improving assessment or understanding of pulmonary physiology in the vast range of pulmonary diseases.
PMID: 24196920 [PubMed - as supplied by publisher]
Source: exp Mol Med - Category: Molecular Biology Authors: Callahan J, Hofman MS, Siva S, Kron T, Schneider ME, Binns D, Eu P, Hicks RJ Tags: Eur J Nucl Med Mol Imaging Source Type: research
More News: Cancer | Cancer & Oncology | CT Scan | Lung Cancer | Molecular Biology | Non-Small Cell Lung Cancer | Perfusion | PET Scan | Physiology | Pulmonary Thromboembolism | Respiratory Medicine | SPECT | Study