Clomipramine, a tricyclic antidepressant, and selegiline, a monoamine oxidase ‐B inhibitor, modulate the activity of phagocytic cells after oral administration in mice

ConclusionsBoth clomipramine and selegiline administered in vivo changed the phagocytic activity of blood cells and IL ‐1β and NO production by murine peritoneal macrophages. This effect depended on the drug, the number of doses and the type of phagocytic cells.

Source: Journal of Pharmacy and Pharmacology - March 8, 2020 Category: Drugs & Pharmacology Authors: Anna Sobieszcza ńska, Magdalena Lis, Agnieszka Suszko‐Pawłowska, Marianna Szczypka Tags: Research Paper Source Type: research