Adequacy of fine-needle aspiration specimens for human papillomavirus infection molecular testing in head and neck squamous cell carcinoma

Conclusion: Our study found that HPV molecular testing is not influenced by percent tumor necrosis or method by which FNA was performed. We believe that a portion of the FNA specimen obtained from head and neck lesions diagnosed as SCC during the rapid on-site evaluation should be sent for HPV DNA testing, independent of the amount of tumor necrosis, thus guaranteeing availability of specimen for HPV testing.

Source: CytoJournal - October 29, 2013 Category: Pathology Authors: Ricardo R LastraMichelle R PramickMegan O NakashimaGregory S WeinsteinKathleen T MontoneVirginia A LiVolsiZubair W Baloch Source Type: research