Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects

ABSTRACT Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion that affects young individuals and deserves attention because it presents an aggressive clinical behavior and high rates of recurrence. This paper aims to report seven cases diagnosed as JOF - age ranging from 11 to 39 years - in a referral center, correlating our findings with clinical and pathological aspects in the literature. The mandible was the most common location, and in three cases, painful symptoms were reported. Regarding the histopathological findings, the majority of cases exhibited a cellularized pattern, and the trabecular subtype was the most commonly found. Regarding treatment, three cases relapsed, and, in two of them, conservative treatments were performed. Accordingly, knowing the clinical-pathological aspects of JOF is important for the correct diagnosis and the establishment of an appropriate treatment that decreases the high recurrence rate of this lesion.RESUMEN El fibroma osificante juvenil (FOJ) es una lesi ón fibro-ósea benigna pocofrecuente que acomete personasjóvenesy merece realce, puespresenta comportamiento clínico agresivo y altas tasas de recidivas. Reportamos siete casos diagnosticados como FOJ - con pacientes entre 11 y 39 anos de edad - en un centro de referencia, relacionando nuestros h allazgos con los aspectos clínicos y patológicos existentes en la literatura. La mandíbula fue la ubicación más común; en tres casos se reportaron síntomas dolo...

Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - March 2, 2020 Category: Pathology Source Type: research