Effect of Ultrasound Intensity and Mode on Piroxicam Transport Across Three-Dimensional Skin Equivalent Epiderm ™.

CONCLUSION: Sonophoresis has a positive effect on enhancing skin permeability. The enhancement level was largely dependent on the sonication factors; frequency, intensity and the length of treatment. Multiple mechanisms of action might be involved in permeation improvement of the piroxicam molecule. Those mechanisms are largely dependent on the ultrasonic conditions. PMID: 32106808 [PubMed - as supplied by publisher]
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research