Insulinoma-associated protein 1 (INSM-1) Expression in Medullary Thyroid Carcinoma FNA: A Multi-Institutional Study

ConclusionINSM-1 nuclear positivity is a reliable marker of MTC neuroendocrine differentiation on cytology material from both primary tumor and metastases. INSM-1 can also discriminate MTC from other primary and secondary thyroid carcinomas when there are cytomorphologic overlaps.
Source: Journal of the American Society of Cytopathology - Category: Cytology Source Type: research