Investigation of cell death mechanism and activity of esculetin ‐loaded PLGA nanoparticles on insulinoma cells in vitro

ConclusionsThe results revealed that esculetin is able to show its anti ‐tumor afficacy after loading to PLGA nano‐micelles and nano‐encapsulation intensifies its cytotoxic activityin vitro. Current study shows that esculetin and its nano formulations are promising agents in treatment of insulinoma.

Source: Journal of Pharmacy and Pharmacology - February 13, 2020 Category: Drugs & Pharmacology Authors: Ayse Karatug Kacar, Fatemeh Bahadori, Serife Evrim Kepekci Tekkeli, Gulacti Topcu, Sehnaz Bolkent Tags: Research Paper Source Type: research