The effect of melatonin on cisplatin-induced nephrotoxicity: a pilot, randomized, double-blinded, placebo-controlled clinical trial

ConclusionsThis study showed that the number of AKI episodes in patients who received melatonin was lower compared to placebo, although it was not found to be statistically significant due to the small sample size. Moreover, melatonin administration in cisplatin recipients reduced tubular kidney injury, evidenced by less increase in KIM-1/creatinine and NGAL/creatinine ratios.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research