Syngeneic Murine Metastasis Models: B16 Melanoma

The murine B16 melanoma is one of the most used tumor models, its application having been used to determine the mechanisms associated with the metastatic process and the development of anticancer therapies. The B16 melanoma was originally established by Fidler and collaborators as a tumor line metastasizing to the lung. Since that time a variety of cell lines have been derived, in vitro or in vivo, having different metastatic behaviors.
Source: Springer protocols feed by Cancer Research - Category: Cancer & Oncology Source Type: news