Genetic Variation across Phenotypic Severity of Autism

Publication date: Available online 6 February 2020Source: Trends in GeneticsAuthor(s): Claudio TomaIt is still unclear how genetic factors of autism spectrum disorder (ASD) are implicated in the significant clinical heterogeneity ranging from intellectual disability (ID) to high-functioning profiles. Here, evidence from recent genetic studies encompassing common and rare variants are combined to suggest a genetic model that may explain the broad gradient of phenotypic severity observed in ASD.

Source: Trends in Genetics - February 8, 2020 Category: Genetics & Stem Cells Source Type: research