Gender specific association of ABCA1 gene R219K variant in coronary disease risk through interactions with serum triglyceride elevation in Turkish adults.

CONCLUSION: R219 allele of the ABCA1 gene independently confers CHD risk in heterozygote Turkish women, not via reduced HDL-C, but interact- ing with elevated TG expressed by the 219K allele, but not in men.
PMID: 24084154 [PubMed - as supplied by publisher]

Source: The Anatolian Journal of Cardiology - September 26, 2013 Category: Cardiology Authors: Coban N, Onat A, Kömürcü Bayrak E, Güleç C, Can G, Erginel Ünaltuna N Tags: Anadolu Kardiyol Derg Source Type: research