The human microbiome in sickness and in health

Publication date: Available online 25 January 2020Source: Revista Clínica Española (English Edition)Author(s): T. Requena, M. VelascoAbstractThe study of the human microbiome has led to an exceptional increase in the current understanding of the importance of microbiota for health throughout all stages of life. Human microbial colonization occurs in the skin, genitourinary system and, mainly, in the oral cavity and intestinal tract. In these locations, the human microbiota establishes a symbiotic relationship with the host and helps maintain physiological homeostasis. Lifestyle, age, diet and use of antibiotics are the main regulators of the composition and functionality of human microbiota. Recent studies have indicated the reduction in microbial diversity as one of the contributors to the development of diseases. In addition to phylogenetic diversity studies, further metagenomic studies are needed at the functional level of the human microbiome to improve our understanding of its involvement in human health.ResumenEl estudio del microbioma humano ha incrementado de manera excepcional el conocimiento actual del que disponemos sobre la importancia de la microbiota en la salud durante todas las etapas de la vida. La colonización microbiana humana ocurre en la piel, en el sistema genitourinario y, principalmente, en la cavidad oral y el tracto intestinal. En todos estos lugares, la microbiota humana establece una relación simbiótica con el hospedador y ayuda a mantener la ...
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research