1, 25-dihydroxy vitamin D3 inhibits Ras-MEK-ERK pathway and regulates proliferation and apoptosis of papillary thyroid carcinoma

Conclusion1, 25-(OH)2D3 can inhibit the activity and promote apoptosis of papillary thyroid carcinoma cell line TPC-1, and its mechanism may be related to the inhibition of Ras-MEK-ERK pathway activity, thus affecting the proliferation and the expression of apoptosis-related proteins.
Source: Steroids - Category: Drugs & Pharmacology Source Type: research