Identifying Missing Biosynthesis Enzymes of Plant Natural Products

Publication date: Available online 21 January 2020Source: Trends in Pharmacological SciencesAuthor(s): Thomas Dugé de Bernonville, Nicolas Papon, Marc Clastre, Sarah E. O’Connor, Vincent CourdavaultElucidating plant-specialized biosynthetic pathways has always constituted a laborious task, notably for natural products with high pharmaceutical values. Here, we discuss emerging omics-based strategies that facilitate the identification of genes from these complex metabolic pathways, paving the way to engineered supplies of these compounds through synthetic biology approaches.
Source: Trends in Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research