Ovarian stem cells: absence of evidence is not evidence of absence

Conclusions: Cysts represent self-renewal and clonal expansion of stem cells with incomplete cytokinesis and are a hallmark feature of stem cells. We suggest the use of PMSG stimulated mouse ovaries and use of more primitive markers like OCT-4 or STELLA rather than MVH for lineage tracing studies to conclusively show presence of stem cells by lineage-tracing studies.
Source: Journal of Ovarian Research - Category: Cancer & Oncology Authors: Source Type: research