An Overview on Recent Patents and Technologies on Solid Dispersion.

This article reviews the various approaches for the preparation of solid dispersion such as a solvent melting, hot-melt extrusion method, solvent evaporation method, cryogenic processing approaches etc. from the perspective of patents filed or granted for these techniques. Some of the aspects taken into account before the preparation of solid dispersions are carrier selection and physic-chemical testing along with an insight into the molecular arrangement of medicaments in solid dispersion. The manuscript further highlights various commercial patented technology platforms such as Solumer<sup>tm</sup>, Hovione, Kinetisol which are based on the concept of solid dispersions. PMID: 31951172 [PubMed - as supplied by publisher]
Source: Recent Patents on Drug Delivery and Formulation - Category: Drugs & Pharmacology Tags: Recent Pat Drug Deliv Formul Source Type: research