Recent advances of long noncoding RNAs involved in the development of multiple sclerosis

Publication date: January 2020Source: Chinese Journal of Natural Medicines, Volume 18, Issue 1Author(s): Qian-Wen LI, Wen LEI, Cong CHEN, Wei GUOAbstractGiven the rapid increase of patients with autoimmune diseases and the lack of satisfactory therapies, the discovery of novel and effective therapeutic targets have been in an urgent demand. Recent studies have revealed that long noncoding RNAs (lncRNAs) play crucial roles in the development of multiple sclerosis (MS), which provides a new opportunity of uncovering novel mechanism associated with the progression of MS. This review highlights the dysregulation of lncRNAs in the development of MS in patients and animal models. Additionally, the potential clinical relevance of lncRNAs severed as therapeutic targets and diagnostic markers are discussed.
Source: Chinese Journal of Natural Medicines - Category: Complementary Medicine Source Type: research