On alcohol disinhibition and inhibition: The intricate relationship between oxidative stress and behavior

Publication date: Available online 15 January 2020Source: Aggression and Violent BehaviorAuthor(s): Tobore Onojighofia ToboreAbstractAlcohol use is known to result in disinhibition. However, evidence suggests that alcohol consumption could also result in inhibition. Several hypotheses have been proposed for this confounding alcohol-induced behavior, but none explains it adequately at the level of the brain. In this paper, oxidative stress is put forth as the underlying cause of alcohol toxicity and behavioral impairments. The implications of this understanding and how oxidative stress influences behavior in obesity, diabetes, psychiatric and neurodegenerative diseases and during hot weather are discussed.
Source: Aggression and Violent Behavior - Category: Psychiatry & Psychology Source Type: research