Back to the beginning: Identifying lesions of diffuse idiopathic skeletal hyperostosis prior to vertebral ankylosis

ConclusionsSmall isolated outgrowths represent the earliest stages of the spinal manifestations of DISH. The use of ESM as an indicator of DISH should be undertaken with great caution until the relationship between these two features is understood.SignificanceImproved accuracy of paleopathological diagnostic criteria of DISH.LimitationsSmall sample comprised of only individuals with DISH.Future researchmicro-CT analysis to investigate the internal structure of the spinal lesions. Analysis of extra-spinal enthesophytes in individuals with and without DISH to understand their pathogenesis and association with the spinal lesions in individuals with DISH.

Source: International Journal of Paleopathology - January 15, 2020 Category: Pathology Source Type: research